May 1, 2025
Cardiovascular Disease Reporter

Good morning. It’s Liz here again, subbing for Theresa on this first day of May. Happy International Workers Day, Beltane, or Mayday to all who celebrate.

Looking ahead, the newest set of Dietary Guidelines for Americans might be coming sooner than their traditional December deadline, Health Secretary Robert F. Kennedy Jr. promised in Wednesday’s cabinet meeting (around the 1:30 mark). He disparaged the scientific advisory committee’s report, calling it “basically unreadable” and “the product of politicized science that drove putting Froot Loops to the top of the food pyramid.” Kennedy’s views aren’t new. Earlier this year committee member Fatima Cody Stanford of Harvard Medical School pushed back, telling me: “When we drew our conclusions, we had to use the literature, not just our own personal beliefs and thoughts and feelings.”

medicine

Trump order zeroing in on 'DEI-based standards' in medical accreditation raises eyebrows

They’re a small but powerful club of groups. Charged with setting standards for the nation’s medical schools and residency programs, two of them find themselves under scrutiny following a Trump administration executive order targeting the use of “DEI-based standards” to accredit universities. The order threatens to revoke federal recognition for accreditors “engaging in unlawful discrimination,” asserting that “the standards for training tomorrow’s doctors should focus solely on providing the highest quality care.” 

Accreditation happens to be a lucrative business; one of the targeted groups reported revenue of $85 million in 2023. The potential loss of federal recognition for the accrediting organizations would be a big deal for hospitals, too: Medicare’s $16 billion to fund residency programs could be at risk if programs are not accredited. 

There’s a larger issue: Compared to their numbers in the general population, Black, Hispanic, and Native American physicians are underrepresented in medicine. The DEI components of accreditation are “just one tiny element among all the others,” one physician told STAT’s Usha Lee McFarling. “Given the outcomes we have, we’re not doing such a great job.” Read more about the threat and its implications.


infectious disease

CDC's annual HIV report is missing crucial data

The CDC posted an annual HIV report on Tuesday. It was slimmer than usual.  The CDC said that a usual estimate of the incidence and prevalence of the epidemic over the last four years was “delayed.” And it did not release an estimate on how widely PrEP, a powerful medicine for preventing HIV, is being used across the country.

On its website, the agency chalked up the missing or delayed reports to last month’s HHS layoffs, which, as STAT previously reported, hit the CDC’s Division of HIV Prevention, or DHP, particularly hard. “As part of this staffing reduction, the DHP branches that produced HIV incidence estimates and provided the statistical expertise needed to assess PrEP coverage were eliminated,” the CDC wrote. “CDC is currently evaluating plans and capacity to resume this work.”

It’s the latest sign of layoff-driven disruption at U.S. health agencies. The FDA appeared to miss a deadline this week for approving or rejecting a drug for a deadly, ultra-rare disease. And at the NIH, researchers were unable to order key reagents and lab tools for long stretches. — Jason Mast


tobacco

Growing teenage use of nicotine pouches

Nicotine pouches are the big new tobacco trend in the U.S.: Philip Morris International shipped 202 million cans of Zyn stateside in the first quarter of 2025, up 53% from the same period a year ago. As with e-cigarettes before them, researchers are monitoring how young people in particular are adopting what they warn are highly addictive products.

A new JAMA Network Open study shows that nicotine pouches are gaining traction among high schoolers. Out of more than 10,000 10th- and 12th-grade students, 5.4% said they'd used nicotine pouches at any point in their lives, compared to 3% the previous year, and 2.6% said they'd used them in the past 30 days, compared to 1.3% the previous year. For now, at least, e-cigarette use is more common: 11.8% of high school students said they'd used them within the past 30 days, compared to 13.4% the previous year. The study also found that nicotine pouches were more popular among male, white, and rural students.

When the FDA authorized the sale of 20 Zyn products in flavors like coffee, citrus, and cinnamon in January of this year, it noted it could revoke that permission if there was a notable increase in youth uptake. The study's authors say that while more monitoring is needed, expanded regulations and public health campaigns "may warrant consideration" for nicotine pouch use. — Sarah Todd



addiction

First it was tranq. Now there’s a new threat in the illegal drug supplyNC-0263_Medetomidine_HCl_10_mg_mL_10_mL_Front__69611_with_BG

STAT

Two years ago, for the first time, many Americans heard about xylazine, aka tranq — a veterinary tranquilizer whose use was rising in Philadelphia, part of an increasingly unsafe illegal drug supply. Now there’s a new ingredient being used to cut fentanyl. A sedative named medetomidine, or “dex,” is once again ravaging people who use it in Philadelphia, along with Pittsburgh, Chicago, and San Francisco.

“We saw our first dexmedetomidine samples in 2022, and it was like: Duh, it’s obvious that this is what’s going to replace xylazine when xylazine gets cracked down on,” Nabarun Dasgupta, a University of North Carolina pharmacoepidemiologist, told STAT’s Lev Facher. Especially troubling are the low heart rates and profound sedation from overdoses and the skyrocketing, potentially organ-damaging elevated heart rate and blood pressure that come with withdrawal.

Read more about this drug’s complicated dangers.


politics

Collins pushes back on Trump's cuts to research 

Wednesday’s Senate hearing on biomedical research began with a rebuke to the Trump administration from a powerful Republican leader and continued on a bipartisan note urging a reversal of federal funding reductions. “Proposed funding cuts, the firing of essential federal scientists, and policy uncertainties threaten to undermine the foundation for our nation’s global leadership,” said Sen. Susan Collins (Maine), the Republican chair of the Senate Appropriations Committee.

The committee’s top Democrat, Sen. Patty Murray (Wash.), echoed Collins’ concerns about maintaining America’s place as the global leader of medical research. “President Trump and Elon Musk have been tossing tomorrow’s groundbreaking cures straight into the shredder,” she said. 

There are few things that Congress does that provide as much hope as NIH funding, Sen. Jerry Moran (Kan.) said, and the Republican warned against the folly of thinking that what happens at NIH doesn’t matter. No representatives from the Trump administration officials testified, but Collins plans to hold another hearing at a date to be determined on the same topic at which administration witnesses will appear. STAT’s John Wilkerson tells us more


politics

Most Americans oppose cuts to health programs Screenshot 2025-04-30 at 10.22.33 AM

Cuts to federal health agencies and programs are unpopular among Americans, mostly across party lines but with some variations, a new KFF Health Tracking Poll out today tells us. Budget and staffing reductions are opposed by large majorities of Democrats (89%) and Independents (67%) while Republicans and Republican-leaning independents are divided on the changes (48% in favor of the cuts, 52% against). But those who say they’re part of the Make America Great Again movement are highly supportive (78%) of cuts to health agency’s staff and budget.

Three quarters (76%) of those surveyed oppose major Medicaid cuts, including just over half of Republicans (55%), most Democrats (95%), and independents (79%). MAGA supporters are split on Medicaid (51% in favor of cuts, 48% opposed).

More opinions: 

  • Most (74%) oppose major cuts to states’ mental health and addiction prevention services: Republicans (58%), Democrats (89%), and independents (75%).
  • Most (71%) oppose major cuts to funding to track infectious disease outbreaks: Republicans (51%), Democrats (89%), and independents (74%).
  • Seven in 10 (69%) oppose major cuts to research at universities and medical centers: Democrats (92%) and Independents (69%) but most Republicans (56%) support the cuts.

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